MALDI-MSGlycobiologyScientist(Laboratory Head)

 

Location: Charleston, South Carolina (on-site)
Start Date: Immediate
Employment Type: Full-time
Compensation: Competitive base salary ($110k–$145k DOE) + benefits + early-stage equity
Base salary expected to be reviewed following successful seed financing.

About the Role

We are an early-stage diagnostics company developing high-throughput MALDI-MS–based clinical assays that leverage the rich biological information encoded in glycobiology and glyco-chemistry–derived biomarkers. Our mission is to translate advanced analytical science into clinically meaningful, scalable diagnostic tests with real impact on patient care. This role offers meaningful autonomy, scientific ownership, and leadership responsibility for the laboratory while remaining closely supported by company leadership.

Key Responsibilities

  • Develop and optimize high-throughput MALDI-MS diagnostic workflows
  • Lead glycan and glycoprotein sample preparation and assay optimization
  • Implement and oversee laboratory automation and liquid-handling workflows
  • Perform downstream MS data processing and analysis (QC, feature extraction, normalization)
  • Establish SOPs and diagnostics-grade documentation standards
  • Support early translational and validation activities for clinical assay development
  • Oversee day-to-day laboratory operations typical of an early-stage environment

Required Skills

  • Hands-on MALDI-MS experience (moderate-to-high throughput preferred)
  • Glycobiology / glyco-chemistry mass spectrometry experience
  • Strong background in biochemistry and assay/sample preparation optimization
  • Experience with laboratory automation or liquid handling systems
  • Familiarity with Python, R, or similar tools for data analysis
  • Ability to work independently with strong documentation practices and leadership mindset

What We Offer

  • The opportunity to work on cutting-edge science at the interface of analytical chemistry, glycobiology, and translational medicine
  • Direct involvement in translating discovery-stage assays into real-world diagnostic applications
  • High scientific ownership and leadership visibility in a growing diagnostics platform
  • Competitive salary, medical/dental/vision benefits, paid time off, and holidays
  • Meaningful early-stage equity participation and growth opportunities as the company scales

How to Apply

Please submit a brief note of interest and your CV. We aim to acknowledge all serious inquiries and respond within 24 hours. 
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