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Posted March 24, 2015
Research Scientist position in a new biotechnology company, GlycoBac, LLC
Contact:
dljarvis@uwyo.edu

Description:
Dr. Donald Jarvis is seeking a motivated individual to serve as a Research Scientist in a new biotechnology company, GlycoBac, LLC  (http://www.glycobac.com/), which was created to refine and commercialize glycoengineered baculovirus-insect cell platforms developed in his academic lab at the University of Wyoming (http://www.uwyo.edu/molecbio/faculty-and-staff/don-jarvis/). The successful candidate will contribute to an overall team effort to create and characterize new baculovirus-insect cell systems that can be used to produce recombinant glycoproteins with humanized glycosylation profiles, as well as other glycoengineering efforts supported by the NIH SBIR program.

Minimal qualifications: Ph.D. and training in laboratory methods in Molecular Biology, Microbiology, Biochemistry, Virology, Glycobiology, Cell Biology, or a related field; primary publications in refereed English language journals; strong written and verbal communication skills.

Preferred qualifications: working laboratory experience in methods of molecular biology, virology, and/or glycobiology, recombinant DNA technology, baculovirus-insect cell systems, protein expression and purification, carbohydrate analysis, vaccine development, and/or therapeutic antibody development.

The successful candidate will work independently on NIH-funded projects involving development and application of glycoengineered baculovirus-insect cell systems for production of vaccines, therapeutic antibodies, and other glycoproteins for direct biomedical applications and studies on the impact of N-glycan structure in clinical efficacy and structural biology. The working environment and lifestyle in Laramie, WY, a small Rocky Mountain Western college town, are simply outstanding. The salary will be at least $40,000 per year, commensurate with qualifications and experience. For more information or to apply for this position, please send a cover letter describing your scientific background, interests, and qualifications, plus a curriculum vitae to:  dljarvis@uwyo.edu, with a reference to GlycoBac RS0315 in the subject line. This position will remain open until a suitable candidate is identified.

GlycoBac, LLC is an Equal Opportunity Employer


Posted December 16, 2014
Postdoctoral position in mass spectrometry for glycoprotein structure
Contact: Joshua Sharp, Ph.D. Complex Carbohydrate Research Center, jsharp@ccrc.uga.edu


Description:
Our laboratory is focused on the development and application of protein chemistry, separation, and mass spectrometry technology for the analysis of 3-D protein structure.  We currently have an opening for a Postdoctoral Research Associate to develop new technologies for hydroxyl radical protein footprinting, with applications directed at probing the structure of HIV gp120 glycoprotein and it's interactions with biomedically important classes of antibodies through a combination of experiment and computational modeling.  Primary responsibilities will be the development and application of technologies to quantitatively characterize proteins by hydroxyl radical footprinting.  The candidate will also be involved in the training of graduate and undergraduate researchers, will lead day-to-day interactions with computational chemists, and will assist in the management of the lab. Candidates with demonstrated experience in protein mass spectrometry, liquid chromatography, protein chemistry and/or protein structure preferred. To apply, please email a cover letter briefly describing your research experience, interests, and goals; a current CV; and a list of at least three references to:

Joshua Sharp, Ph.D.
Complex Carbohydrate Research Center
jsharp@ccrc.uga.edu


Posted December 9, 2014
Postdoctoral position studying newly discovered rare disease
Contact: azimmon@sanfordburnham.org


Description:

NGLY1 mutations cause a human neurological disease of protein de-glycosylation. Pathological mechanisms are unknown

This position requires significant publications in biochemistry, cell biology, glycobiology, ERAD or cytoplasmic protein degradation. Fluent spoken and written English, independent thinking, and team spirit are essential.

To respond, please send a single PDF document that includes all of the following: your current CV; a 2 page letter outlining your background, specific interest in NGLY1, and how you would study it; and 3 reference letters discussing your specific qualifications for this project.  Only those applicants who apply in this manner will be considered.

Please submit application materials to: azimmon@sanfordburnham.org

NGLY1 background articles: PMID 24651605 and http://www.newyorker.com/magazine/2014/07/21/one-of-a-kind-2




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