Session Titles link to Abstracts from the Session
	Wednesday, November 15
8:30 am – 12:30 pm	SATELLITE SYMPOSIUM I: NEW TECHNOLOGIES FOR GLYCOMICS Organized by Richard Cummings, Emory University and Michael Pierce, University of Georgia
1:30 pm – 5:00 pm	SATELLITE SYMPOSIUM II: THERAPEUTIC RECOMBINANT GLYCOPROTEINS – PRODUCTION, PURIFICATION, AND ANALYTICAL METHODS Organized by Joseph Siemiatkoski, Biogen Idec and Shekar Ganesa, Genzyme
7:00 – 7:10 pm	CONFERENCE OPENING Opening Remarks: Linda G. Baum, President, Society for Glycobiology
7:10 – 9:00 pm	SESSION I: GLYCAN – MEDIATED CELLULAR SIGNALING, Grand Ballroom Chair, Jim Dennis, University of Toronto • 7:10pm Decoding the Structure-Activity Relationships of Glycosaminoglycans in the Brain; Linda C. Hsieh-Wilson; Caltech and HHMI, Pasadena, CA • 7:30pm Inflammatory Signaling by the C-type Lectin Recpetor Dectin-1; David M. Underhill; Cedars-Sinai Medical Center, Los Angeles, CA • 7:50pm Deciphering the 'O-GlcNAc Code': Lessons from C. elegans and Human disease; John A. Hanover; NIDDK, National Institutes of Health, Bethesda, MD • 8:10pm CD33 type Siglecs are Degraded by the SOCS3 via ECS E3 Ligase; Jim Johnston; Queen's University Belfast, Belfast, Northern Irelan • 8:30pm Modulation of Normal Signaling by Shed Tumor Gangliosides.; Stephan Ladisch; Children's National Medical Center, Washington, DC  • 8:50pm N-glycan Processing Integrates Cellular Responsiveness to Extracellular Cues in Cancer Progression And T Cell Activation; Ken Lau1; Emily A. Partridge1; Pamela Cheung1; Cristina I. Silvescu2; Ani Grigorian3; Vernon N. Reinhold2; Michael Demetriou3; James W. Dennis1; 1Mount Sinai Hospital, Toronto, Canada; 2University of New Hampshire, Durham, NH; 3University of California, Irvine, CA • 8:55pm N-Acetylglucosaminyltransferase III Antagonizes N-Acetylglucosaminyltransferase V on Alpha3beta1 Integrin-Mediated Cell Migration; Yanyang Zhao1; Jianguo Gu1; Takatoshi Nakagawa1; Akihiro Kondo1; Nana Kawasaki2; Eiji Miyoshi1; Naoyuki Taniguchi1; 1Osaka University Graduate School of Medicine, Osaka, Japan; 2National Institute of Health Sciences, Tokyo, Japan
9:00 – 10:00 pm	WELCOME RECEPTION

	Thursday, November 16
8:30 – 10:20 am	SESSION II: GLYCAN BIOSYNTHESIS, PROCESSING AND RECOGNITION, Grand Ballroom Chair, Karen Colley, University of Illinois • 8:30am A Key Enzyme in Protein N-glycosylation: Oligosaccharyl Transferase; Manasi Chavan1; Guangtao Li1; Zhiqiang Chen2; Huilin Li2; Hermann Schindelin3; William J. Lennarz1; 1Stony Brook University, Stony Brook, NY; 2Brookhaven National Laboratory, Upton, NY; 3Würzburg University, Würzburg, Germany • 8:50am Structural Snapshots of the Mannose 6-Phosphate Receptors; Nancy M. Dahms; Medical College of Wisconsin, Milwaukee, WI • 9:10am The “Lipid-linked Oligosaccharide/CDG-I/ER Stress Response” Triad; Mark A. Lehrman; UT-Southwestern Medical Center, Dallas, TX • 9:30am Requirement of Fatty Acid Remodeling for Raft-association of GPI-anchored Proteins.; Taroh Kinoshita1; Yuko Tashima1; Toshiaki Houjou2; Morihisa Fujita3; Takehiko Yoko-o3; Yoshifumi Jigami3; Ryo Taguchi2; Yusuke Maeda1; 1Osaka University, Osaka, Japan; 2University of Tokyo, Tokyo, Japan; 3Natl Inst of Adv Indust Sci and Technol, Tsukuba, Japan • 9:50am Glycan Biosynthesis, Processing and Recognition; Jonathan Weissman; UCSF, San Francisco, CA • 10:10am A DHHC protein regulates activity and subcellular transport of GalNAc transferase B in Drosophila melanogaster; Anita Stolz1; Benjamin Kraft1; Manfred Wuhrer2; Cornelis H. Hokke2; Rita Gerardy-Schahn1; Hans Bakker1; 1Medizinische Hochschule Hannover, Zelluläre Chemie, Hannover, Germany; 2Leiden University Medical Centre, Parasitology, Leiden, The Netherlands • 10:15am The Mammalian and Drosophila Orthologous UDP-GalNAc: polypeptide α-N-acetylgalactosaminyltransferases (ppGalNAc-Ts) T1 and T2 Possess Highly Conserved Peptide Substrate Specificities; Thomas A. Gerken1; Oliver Jamison1; Kelly G. Ten Hagen2; 1Case Western Reserve Univ., Cleveland, OH; 2National Institutes of Health, NIDCR, Bethesda, MD
10:45 am – 12:35 pm	SESSION III: DEVELOPMENTAL GLYCOBIOLOGY Grand Ballroom Chair, Jeff Esko, UCSD • 10:45am Roles for O-Fucose and Pofut1 in Notch Signaling in Mammals; Pamela Stanley; Changhui Ge; Mark Stahl; Kazuhide Uemura; Shaolin Shi; Albert Einstein College Medicine, New York, NY • 11:05am Mind the Gap! Glyco-therapies for Enteric Protein Loss; Hudson H Freeze; The Burnham Institute for Medical Research, La Jolla, CA • 11:25am O-Glycosylation of Cysteine-Knot Motifs; Robert S. Haltiwanger; Malgosia Dlugosz; Yi Luo; Kelvin Luther; Aleksandra Nita-Lazar; Nadia Rana; Hideyuki Takeuchi; Bernadette C. Holdener; Stony Brook University, Stony Brook, NY • 11:45am Analysis of the Conserved Oligomeric Golgi (COG) Complex; Monty Krieger; MIT, Cambridge, MA • 12:05pm Developmental Regulation of HSPG Synthesis during Drosophila Embryogenesis; Douglas Bornemann; Sangbin Park; Rahul Warrior; UC Irvine, Irvine, CA • 12:25pm Unlike Mammalian GRIFIN, the Zebrafish Homologue (DrGRIFIN) may Represent a Functional Carbohydrate-Binding Galectin; Hafiz Ahmed; Gerardo R. Vasta; Center of Marine Biotechnology, UMBI, Baltimore, MD • 12:30pm A Mucin-type O-Glycosyltransferase is required during Multiple Stages of Drosophila Development; E Tian; Kelly G. Ten Hagen; NIDCR, NIH, Bethesda, MD
2:00 – 4:00 pm	POSTERS and EXHIBITS
4:00 – 6:15 pm	SESSION IV: NOVEL ANALYTICAL TECHNIQUES – SYNTHESIS, VALENCY, AND ARRAYS Grand Ballroom Chair, Anne Dell, Imperial College, London • 4:00pm Lectins Bind to Multivalent Glycoproteins with a Large Gradient of Binding Constants; Curtis F. Brewer; Tarun K. Dam; Albert Einstein College of Medicine, Bronx, NY • 4:20pm Using Glycodendrimers to Study Protein-carbohydrate Interactions; Mary J Cloninger; Montana State University, Bozeman, MT • 4:40pm Automated Oligosaccharide Synthesis and the Direct Formation of Carbohydrate Microarrays; Nicola L. Pohl; Iowa State University, Ames, IA • 5:00pm Structure/thermodynamic Relationship in Lectin/glycan Interaction. Strategies for High Affinity Binding; Anne Imberty; CERMAV-CNRS, Grenoble, France • 5:20pm Specificity of Glycosaminoglycan Binding to CCR2 Chemokines: Significance of Sulfation Binding Sites; Julie Leary; University of California, Davis, CA • 5:40pm Influenza HA Structure and Receptor Binding using the Glycan Microarray; Ian A. Wilson; James Stevens; Ola Blixt; James Paulson; The Scripps Research Institute, La Jolla, CA • 6:00pm Heterobivalent Ligands: A Versatile Approach to Ligand Induced Protein Aggregation Exemplified by the Structure-based Design of Shiga Toxin Antagonists; Pavel Kitov; David Bundle; University of Alberta, Edmonton, Alberta • 6:05pm New Mass Spectrometry Tools for Glycosaminoglycans Analysis; Bérangère Tissot1; Stuart M. Haslam1; Howard R. Morris1; Jeremy E. Turnbull2; Andrew K. Powell2; Zheng-liang Zhi2; John T. Gallagher3; Christopher J. Robinson3; Anne Dell1; 1Imperial College, London, UK; 2University of Liverpool, Liverpool, UK; 3University of Manchester, Manchester, UK

	Friday, November 17
8:30 – 10:00 am	SESSION V: GLYCANS IN NEUROBIOLOGY – DEVELOPMENT AND FUNCTION Grand Ballroom Chair, Ron Schnaar, Johns Hopkins University • 8:30am Sialoglycans Regulate Axon Regeneration after Central Nervous System Injury – the Therapeutic Potential of Sialidase; Andrea Mountney1; Lynda J.S. Yang2; Matthew R. Zahner1; Ileana Lorenzini1; Katarina Vajn1; Lawrence P. Schramm1; Ronald L. Schnaar1; 1The Johns Hopkins School of Medicine, Baltimore, MD; 2University of Michigan, Ann Arbor, MI • 8:50am β1,3-N-acetylglucosaminyltransferase 1 is required for Axon Pathfinding by Sensory Neurons; Gary Schwarting; Tim Henion; Univ of Massachusetts Medical Sch - Shriver Center, Waltham, MA • 9:10am The LARGE Glycosyltransferase Family; Jane E Hewitt; University of Nottingham, Nottingham, UK • 9:30am Role of Glypican-1 in Brain Development; Yi-Huei Linda Jen, Michele Musacchio, and Arthur D. Lander; Dept. of Developmental & Cell Biology, Univ. of California, Irvine, CA • 9:50am N-Acetylmannosamine Treatment Rescues a Mouse Model of Hereditary Inclusion Body Myopathy; Marjan Huizing1; Riko Klootwijk1; Belinda Galeano1; Irini Manoli1; Mao-Sen Sun1; Carla Ciccone1; Daniel Darvish2; Donna Krasnewich1; William A Gahl1; 1NIH, NHGRI, Bethesda, MD; 2HIBM Research Group, Encino, CA • 9:55am GnT-Vb Expression Increases O-Mannosyl-linked HNK-1 Epitope Leading to Changes in Neuronal Cell Adhesion and Migration; Karen L. Abbott1; Karolyn Troupe1; Rick T. Matthews2; Michael Pierce1; 1Complex Carbohydrate Research Center, UGA, Athens, GA; 2Yale University, New Haven, CT
10:30 am – 12:30 pm	SESSION VI: GLYCANS IN MICROBIAL PATHOGEN-HOST INTERACTIONS Grand Ballroom Chair, Sam Turco, University of Kentucky • 10:30am Modulation of the Host Immune Response by Schistosome Glycoconjugates; Ellis Van Liempt1; Sandra Meyer2; Sandra J. Van Vliet1; Anneke Engering1; Boris Tefsen1; Caroline M.W. Van Stijn1; Rudolf Geyer2; Yvette Van Kooyk1; Irma Van Die1; 1VU University Medical Center, Amsterdam, the Netherlands; 2Justus Liebig University, Giessen, Germany • 10:50am Role of M. tuberculosis Cell Wall Carbohydrates in Host Adaptation; Larry S. Schlesinger; The Ohio State University, Columbus, OH • 11:10am The Glycobioloy of Nipah Virus Entry; Benhur Lee; University of California, Los Angeles, Los Angeles, CA • 11:30am Immune Recognition of Candida Albicans: The Taste of a Fungus; Neil Gow; University of Aberdeen, Aberdeen, U.K • 11:50am Arenaviruses Mimic the Molecular Mechanism of Receptor Recognition used by alpha-Dystroglycans’s Host-Derived Ligands; Jillian M. Rojek1; Kevin P. Campbell2; Stefan Kunz1; 1The Scripps Research Institute, L a Jolla, CA; 2Howard Hughes Medical Institute University of Iowa, Iowa City, IA • 12:10pm Functional Glycoproteomic Analysis of Caenorhabditis elegans Interaction with Bacterial Pathogens; Jenny Tan; Hui Shi; Harry Schachter; Hospital for Sick Children, Toronto, Canada • 12:15pm Inhibition of Helicobacter pylori binding by Lewis b or Sialyl-Lewis x Carrying Recombinant Mucin-type Proteins Produced by Glyco-engineered CHO Cells; Anki Gustafsson1; Jining Liu1; Rolf Sjöström2; Håkan Yildirim1; Elke Schweda1; Michael E. Breimer3; Thomas Borén2; Jan Holgersson1; 1Karolinska Institutet, Stockholm, Sweden; 2Umeå University, Umeå, Sweden; 3Sahlgrenska University Hospital, Göteborg, Sweden
2:00 – 4:00 pm	POSTERS and EXHIBITS
4:00 – 4:30 pm	BUSINESS MEETING
4:30 – 5:30 pm	KARL MEYER LECTURE Emerging Roles of O-GlcNAc as a Nutrient/Stress Sensor Globally Regulating Signaling, Transcription, and Protein Turnover; Gerald W. Hart; Chad Slawson; Mike Housley; Quira Zeidan; Stephen Whelan; Wagner Dias; Win Cheung; Kaoru Sakabe; Pui Butkinaree; Kyoungsook Park; Shino Shimoji; Zihao Wang; John Bullen; Johns Hopkins Medical School, Baltimore, MD
7:00 – 9:30 pm	BANQUET. Nominal fee. Extra tickets for guests may be ordered.

	Saturday, November 18
8:30 – 10:00 am	SESSION VII: GLYCANS IN CANCER – PROGNOSIS TO THERAPY Grand Ballroom Chair, Joe Lau, Roswell Park Cancer Institute • 8:30am On the Role of Galectin-3 in Cancer Metastasis; Avraham Raz; Wayne State University, Karmanos Cancer Institute, Detroit, MI • 8:50am The role of Glycosphingolipid Gb3 in Colon Cancer Invasiveness; Olga Kovbasnjuk1; Rakhilya Murtazina1; Oksana Gutsal1; Anne Kane2; Mark Donowitz1; 1Johns Hopkins School of Medicine, Baltimore, MD; 2Tufts New England Medical Center, Boston, MA • 9:10am Glycans in Cancer – Prognosis to Therapy; Steve Rosen; UCSF, San Francisco, CA • Development and Characterization of Peptide Mimics of TF-Antigen; Jamie Heimburg1; Adel Almogren1; Sue Morey1; Olga V. Glinskii2; Virginia H. Huxley2; Vladislav V. Glinsky2; Rene Roy3; Richard Cheng1; Kate Rittenhouse-Olson1; 1University at Buffalo, Buffalo, NY; 2University of Missouri, Columbia, MO; 3University of Quebec at Montreal, Montreal, Canada • 9:35am Expression of Tn and SialylTn Antigens in Human Tumor Cell Lines Raised from Mutation in Molecular Chaperone Cosmc; Tongzhong Ju1; Grainger Lenneau2; Tripti Gautam2; Yingchun Wang1; Doris Benbrook2; Marie H. Hanigan2; Richard D. Cummings1; 1Emory University School of Medicine, Atlanta, Georgia; 2The University of Oklahoma health Sciences Center, Oklahoma City, Oklahoma • 9:40am Glycoprotoemic Changes In Human Blood Serum Associated with Breast Cancer; Yehia Mechref1; Milan Madera2; Benjamin Mann2; Iveta Klouckova2; Milos V. Novotny1; 1National Center for Glycomics and Glycoproteomics, Bloomington, IN; 2Dept of Chemistry, Indiana Universtiy, Bloomington, IN
10:30 am – 12:30 pm	SESSION VIII: GLYCAN CONTROL OF LEUKOCYTE MIGRATION AND FUNCTION IN INFLAMMATION Grand Ballroom Chair, Robert Sackstein, Harvard University • 10:15am Mechanisms of Cell Adhesion through Selectin-glycan Interactions Under Flow; Rodger McEver; Oklahoma Medical Research Foundation, Oklahoma City, OK • 10:35am Transcriptional Basis for Selectin Ligand Expression by Th1 Cells; Geoffrey S. Kansas; Northwestern Medical School, Chicago, IL • 10:55am 6-Sulfo sialyl Lewis X on both N- and O-Glycans Play Critical Roles as L-Selectin Ligands; Minoru Fukuda; Bunham Institute for Medical Research, La Jolla, CA • 11:15am Sialylation-dependent Regulation of α4β1 Integrin Receptors; Alencia V Woodard-Grice; Alexis C McBrayer; Susan L Bellis; University of Alabama at Birmingham, Birmingham, AL • 11:20am Platelets generate inflammatory and angiogenic fragments of hyaluronan; Carol de la Motte1; Julie Nigro1; Amit Vasanji1; Hyunjin Rho1; Sudip Bandyopadhyay1; Robert Stern2; 1Cleveland Clinic, Cleveland, OH; 2UC San Francisco, San Francisco , CA
2:00 – 4:00 pm	POSTERS and EXHIBITS
4:00 – 6:00 pm	SESSION IX: GLYCANS IN IMMUNE DEVELOPMENT AND FUNCTION Grand Ballroom Chair, Linda Baum, UCLA • 4:00pm NKT Cells Recognize Different Types of Bacterial Glycolipids; Mitchell Kronenberg1; Emmanuel Tupin1; Yuki Kinjo1; Douglass Wu2; Masakazu Fujio2; Moriya Tsuji3; Timothy Sellati4; Dirk Zajonc2; Ian Wilson2; Chi-huey Wong2; 1La Jolla Inst. Allergy & Immunol, La Jolla, CA; 2Scripps Research Institute, La Jolla, CA; 3Rockefeller University, New York, NY; 4Albany Medical College, Albany , NY • 4:20pm Mammalian N-Glycosylation Inhibits Innate Immune Mechanisms that Induce and Mediate Autoimmune Disease; Ryan S. Green; Jamey D. Marth; Howard Hughes Medical Institute, UCSD, La Jolla, CA • 4:40pm Dendritic Cells and the Recognition of Glycan Structures to Mediate Cellular Communication and Immune Responses; Yvette van Kooyk; Molecular Cellbiology and Immunology, VUmc, Amsterdam, the Netherlands • 5:00pm Glycans in Immune Development and Function; Carrie Miceli; UCLA, Los Angeles, CA • 5:20pm Role of Protein Mannosylation in Linking Innate and Adaptive Immune Responses to Fungi; Stuart M Levitz; UMass Medical Center, Worcester, MA

Sunday, Nov 19

8:00 am Studio I/II Participating Investigators of the Consortium for Functional Glycomics   November 19, 2006 8:30 am - 2:30 pm   Attendance is open to all interested scientists and is free of charge. Heading into the next funding period, the CFG plans to focus Participating Investigator (PI) meetings on the biology of glycan-protein interactions. This first PI meeting of the new funding period will focus on "Glycan binding proteins: Biological insights from glycan microarrays" and will include presentations by PIs using CFG resources. Attendees will also be updated on progress at the CFG during the last year, including the glycomics initiative and updates to the databases. New initiatives for the coming years will be presented. There will be an opportunity for PIs to provide feedback on the generation of resources and on initiatives such as the creation of a reagent bank. The agenda can be found at http://glycomics.scripps.edu/PI2006Agenda.pdf Please notify Anna Crie (annacrie@scripps.edu)of your intention to attend on or before October 31, 2006.