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 Important Dates Minimize

Deadline Item
Friday, July 19, 2002 Submission of Abstracts
Thursday, August 01, 2002 Karl Meyer Award Nominations
Thursday, August 01, 2002 Travel Stipend Applications
Wednesday, October 09, 2002 Advance Rate Conference Registration
Wednesday, October 09, 2002 Advance Rate Hotel Reservations
Thursday, October 10, 2002 Web Publication of Abstracts
Saturday, November 09, 2002 Satellite Meetings
Saturday, November 09, 2002 Meeting Starts
Tuesday, November 12, 2002 Meeting Ends

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 Program Minimize

Saturday, November 9
7:00 - 8:30 pm CONFERENCE OPENING
  • Welcome: James Paulson, The Scripps Research Institute
  • Keynote Address: Kurt Drickamer, University of Oxford. A Genomic View of Carbohydrate-Recognition Proteins
8:30 - 10:00 pm WELCOME RECEPTION
Sunday, November 10
8:30 - 10:10 am CRP-1: C-TYPE LECTINS Chair: Richard D. Cummings, University of Oklahoma

Invited Speakers

  • Yvette van Kooyk, VU Medical Center. Immune Function of C-Type Lectins on Dendritic Cells.
  • Sem Saeland, Schering-Plough Research. Langerin, a C-Type Lectin of Langerhans-Type Dendritic Cells: A Pathway for Processing or Retention of Glycosylated Antigens?
  • Nobutaka Wakamiya, Asahikawa Medical College. Roles of the Membrane Type Collectin CL-P1 in Vascular Endothelial Cells.
Short Talks
  • Irma Van Die, VU Medical Center. The dendritic cell specific C-type lectin DC-SIGN recognizes Lewis x, a major glycan epitope of Schistosoma mansoni egg antigen
  • Anne Leppanen, University of Oklahoma. Binding of L-selectin to a glycosulfopeptide requires tyrosine sulfation.
  • Noorjahan Panjwani, Tufts University School of Medicine. Galectin-3 and -7, but not galectin-1, play a role in re-epithelialization of wounds
10:10 - 10:40 am BREAK
10:40 - 12:20 pm MEDICAL GLYCOBIOLOGY Chair: Hudson Freeze, The Burnham Institute

Invited Speakers

  • Ram Sasisekharan, Massachusetts Institute of Technology. Dynamic Regulationof Tumor Growth and Metastasis by Heparan Sulfate Glycosaminoglycans.
  • Jeff Esko, University of California, San Diego. A Murine Model for Hereditary Multiple Exostosis (HME).
  • John S. Logan, VP Research, DNX Corp. Overcoming Glycosylation Dependent Acute Rejection in Xenotransplantation.
Short Talks
  • Stephan Hinderlich, Institut für Molekularbiologie und Biochemie. Is hereditary inclusion body myopathy a glycosylation disease?
  • Roy Jefferis, University of Birmingham. Glycosylation of therapeutic monoclonal antibodies: structural features and biological consequences.
  • Tomio Yabe, Tokyo Metropolitan Institute for Neuroscience. Brain specific 3OST isoforms facilitate cellular entry of Herpes virus I.
12:20 - 2:00 pm LUNCH BREAK
2:00 - 4:00 pm POSTER SESSION AND EXHIBITS
4:00 - 4:30 pm Karl Meyer Award Lecture
4:30 - 6:10 pm CRP-2:SELECTINS Chair: Kurt Drickamer, University of Oxford.

Invited Speakers

  • John Lowe, University of Michigan Medical Center. Selectin ligands and leukocyte biology.
  • Geoffrey Kansas, Northwestern University Medical School. Control of Selectin Ligand Biosynthesis in Activated T Cells.
  • Uli von Andrian, Harvard Medical School. In Vivo Analysis of Endothelial Selectin Ligands.

Short Talks

  • Hiroto Kawashima, The Burnham Institute. High Endothelial Venule-Restricted Sulfotransferase and Core 2 Branching b1,6-N-acetylglucosaminyltransferase Exert Collaborative, Dominant Control Over Lymphocyte Homing.
  • Junya Mitoma, The Burnham Institute. Sialyl Lewis x in extended core1 mucin-type O-glycans: Novel L-selectin ligand in neutrophil-neutrophil interaction.
  • Karen R. Snapp, Northwestern Medical School. Structural modifications of PSGL-1 required for adhesion and entry of the causative agent of Human Granulocytic Ehrlichiosis (HGE).
Monday, November 11
8:30 - 10:10 am GLYCOIMMUNOLOGY: NEW DIRECTIONS Chair: Linda Baum, University of California, Los Angeles.

Invited Speakers

  • Ellis Reinherz, Harvard Medical School and Dana Farber Cancer Institute. Glycobiology and Immune Recognition by T Lymphocytes.
  • Santos Mañes, Universidad Autonoma de Madrid. Role of Glycosphingolipid-Enriched Membrane Raft Domains in the Polarization of Migrating Cells.
  • Ian Wilson, The Scripps Research Institute. Carbohydrate Recognition in the Immune System.

Short Talks

  • Shihao Chen, The Burnham Institute. Natural Killer Cells Attack Tumor Cells Expressing High Levels of Sialyl Lewis x Oligosaccharides.
  • Ardythe L. Morrow, Cincinnati Children's Hospital Medical Center. Human Milk Oligosaccharide Homologs of Lewis Blood Group Epitopes and Protection against Diarrhea in Breastfed Infants.
  • Pauline M. Rudd, University of Oxford. A novel form of carbohydrate recognition. The broadly neutralizing Anti-HIV-1 antibody 2G12 recognizes a cluster of a1-2 mannose residues on the outer face of GP120.
10:10 - 10:40 am BREAK
10:40 - 12:20 pm GLYCOMICS Chair: Vernon Reinhold, University of New Hampshire.

Invited Speakers

  • Anne Dell, Imperial College of Science, Technology & Medicine. Ultra-High Sensitivity Screening of the Glycomes of Mammals and Model Organisms.
  • Nicolle Packer, Proteome Systems Ltd. Glycoproteomics: Realistic Expectations.
  • Willi von der Lieth, Deutsches Krebsforschungszentrum. Developing Bioinformatics Tools for Glycomics.

Short Talks

  • John F. Cipollo, Boston University, Goldman School of Dental Medicine. The Fine Structure of Caenorhabditis elegans N-glycans.
  • Heidi A. Geiser, University of New Hampshire.HTP Proteome-Glycome Analysis in Caenorhabditis elegans.
  • Elena M. Comelli,The Scripps Research Institute. A comprehensive study of glycosyltransferase gene expression at different stages of lymphocyte activation.
12:20 - 2:00 pm LUNCH BREAK
12:30 - 2:00 pm Board of Directors Meeting
2:00 - 4:00 pm POSTER SESSION AND EXHIBITS
4:00 - 5:40 pm DEVELOPMENTAL GLYCOBIOLOGY Chair: Jeff Esko, University of California School of Medicine, San Diego.

Invited Speakers

  • Minoru Fukuda, The Burnham Institute. Roles of Polysialic Acid in Neural Development and Cancer.
  • Paul Martin, University of California School of Medicine, San Diego. Role of Dystroglycan Glycosylation in Neuromuscular Development and Muscular Dystrophy.
  • Robert S. Haltiwanger, State University of New York at Stony Brook. O-Linked Glycosylation of EGF Repeats in Development: Effects of O-Fucose on Notch and Nodal Signaling.

Short Talks

  • Kenneth Irvine, Howard Hughes Medical Institute. Regulation of Notch signaling by O-fucose glycans.
  • Firoze B. Jungalwala, E. K. Shriver Center at University of Massachusetts Medical School. Glucuronyl glycoconjugates replace the functions of sulfoglucuronyl glycoconjugates in the HNK-1 sulfotransferase null mutant mice.
  • Wei-hsuan Yu, Harvard Medical School. A lesson From CD44HSPG Null Mice: Heparan sulfate mediate CD44HSPG transactivating erbB4 pathway implicating the survival mechanism for epithelial/smooth muscle cells during the postpartum reproductive organism extra cellular matrix remodeling.
5:40 - 6:10 pm Society Business Meeting
7:00 - 9:00 pm CONFERENCE BANQUET
Tuesday, November 12
8:30 - 10:10 am CRP-3: SIGLECS Chair: Paul Crocker, Wellcome Trust Biocentre School of Life Sciences, Dundee University.

Invited Speakers

  • Paul Crocker, Wellcome Trust Biocentre School of Life Sciences, Dundee University. Probing the Signaling Properties of CD33-Related Siglecs Expressed on Myeloid Cells
  • Takashi Angata, University of California School of Medicine, San Diego. Evolutionary Considerations in Understanding Siglec Biology.
  • Ronald Schnaar, The Johns Hopkins School of Medicine. Nerve Cell Signaling Induced by MAG/Siglec-4 Binding to Gangliosides.

Short Talks

  • Lars Nitschke, Institute of Virology and Immunobioloy, University of Wuerzburg. Sialic-acid binding of CD22 is required for inhibition of the BCR signal.
  • Yuzuru Ikehara, The Scripps Research Institute. Analysis of Siglec 7 and 9 subcellular localization following TCR stimulation.
  • Brian E. Collins, The Scripps Research Institute. Sialoside Modulation of CD22 Function.
  • Soerge Kelm, University Bremen. Sialic acid derivatives as probes for biological functions of Siglecs.
10:10 - 10:40 am BREAK
10:40 - 12:20 pm FRONTIER TOPICS Chair: Pamela Stanley, Albert Einstein College Medicine.

Invited Speakers

  • Gerald Hart, Johns Hopkins University School of Medicine. Dynamic Interplay Between O-GlcNAc and phosphorylation: Roles in Signaling, Stress Responses, and Transcription.
  • Marilynn Etzler, University of California Davis. Perception of the Oligosaccharide Signal that Initiates the Rhizobium-Legume Symbiosis.
  • Hudson Freeze, The Burnham Institute. Anti-carboxylate antibody mAbGB3.1 blocks onset of Th-1 mediated murine colitis.

Short Talks

  • Mark A. Lehrman, UT-Southwestern. Glycogen Phosphorylase, A Candidate Mediator Of Enhancement Of Lipid-linked Oligosaccharide Extension By The Endoplasmic Reticulum Unfolded Protein Response.
  • Aleksandra Furmanek, Friedrich Miescher Institute. C-mannosylation of the erythropoietin receptor.
  • Toshisuke Kawasaki, Graduate School of Pharmaceutical Sciences, Kyoto University. Requirement of the HNK-1 Carbohydrate for Synaptic Plasticity and Spatial Learning.
12:20 - 2:00 pm LUNCH BREAK
2:00 - 4:00 pm POSTER SESSION AND EXHIBITS
4:00 - 6:00 pm REGULATION OF GLYCOSYLATION Chair: James Paulson, The Scripps Research Institute.

Invited Speakers

  • Richard Cummings, University of Oklahoma Health Science Center. Chaperone Function in Regulating O-Glycan Biosynthesis.
  • Henrik Clausen, Faculty of Health Sciences, University of Copenhagen. More Functions to the Polypeptide GalNAc-Transferases than Meets the Eye.
  • Barbara Imperiali, Massachusetts Institute of Technology. Asparagine-Linked Glycosylation: Causes and Consequences.
  • Armando Parodi, Institute for Biotechnological Research University of San Martin. Protein-Protein and Protein-Glycan Interactions in the Recognition of Glycoprotein Conformers.

Short Talks

  • Michiko N. Fukuda, The Burnham Institute. Importance of complex type N-glycans in spermatogenesis and neonatal survival: studies of a-mannosidase IIx (MX)-knock out and a-mannosidase II (MII)/MX double knock out mice.
  • Emily A. Partridge, Samuel Lunenfeld Research Institute, Mount Sinai Hospital. Regulation of cytokine receptor endocytosis and signal transduction by N-acetylglucosaminyltransferase V (Mgat5).
  • Qi Yan, SUNY at Stony Brook. Studies on the Function of Stt3p, an Essential Subunit of Oligosaccharyl Transferase.
6:00 pm FAREWELL TOAST

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